According to the panel, there is evidence to support the efficacy of Econase
XT in improving production parameters in chickens for fattening at 8,000BXU per
kg, and turkeys for fattening at 16,000BXU per kg. This evidence is extended to
chickens reared for laying and turkeys reared for breeding at the corresponding
dose.
Econase XT was tolerated at 10 times (turkeys) the maximum
recommended dose (24,000BXU per kg) and so it is safe for these target species
at the proposed conditions of use.
The experts had no concerns regarding
consumer safety when the product is used as an additive in animal feed based on
the absence of adverse effect in two mutagenicity/clastogenicity tests and a
sub-chronic oral toxicity study.
Econase XT is an enzyme feed additive
with endo-1,4-beta xylanase as its declared activity. The production strain is a
genetically modified strain of Trichoderma reesei.
Related
links:
EFSA
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